Hard Tissue Research Laboratory - Dental Research Organizations

Hard Tissue Research Laboratory
At the Hard Tissue Research Laboratory we investigate bone by using the Donath/EXAKT technique of undecalcified histotechnology. The majority of the research with which we're concerned involves implants. We also study various bone grafting materials and techniques. A new area of research is bone augmentation and growth enhancement using various bone promoting peptides and other natural or genetically engineered chemicals.
Bone specimens are dehydrated, infiltrated, and then embedded in a light curing resin. Very thin sections are possible and we generally use 35痠 to 50痠 sections for the final examination. The primary focus of many of our research projects is the implant/tissue interface. In this way, we are able to assess the osseointegration of the bone and metal surface. Final specimens are stained with various stains that emphasize the relative maturity of the bone as well as differentiate between vital, non-vital, calcified, and non-calcified bone elements. Computer assisted image analysis allows us to obtain histomorphometric information. This is especially useful in analyzing bone cores to determine the percentage of vital bone, non-vital grafted bone, and non-bone materials such as various types of hydroxyapatite (HA). Fluorescence microphotography of fluorochrome labelled bone specimens is also common.
Office Hours
Monday-Friday 8:00A.M. - 5:00P.M. Central Time
Telephone: Dr. Rohrer 612-624-5478
Hari Prasad 612-626-2190
Fax: 612-626-3076
Email: rohre008@umn.edu
Contact
Hari Prasad - Research Scientist
Phone: 612-626-2190
E-mail: prasa012@umn.edu
Cell: 763-639-8181
Michael Rohrer - Director
Phone: 612-624-5478
E-mail: rohre008@umn.edu