Correlation of peri-implant health and myeloperoxidase levels: a cross-sectional clinical study

Correlation of peri-implant health and myeloperoxidase levels: a cross-sectional clinical study
October 2004
Stanislav Liskmann1,2, Mihkel Zilmer2, Tiiu Vihalemm2, Olev Salum1 and Krista Fischer3
Clinical Oral Implants Research
Volume 15 Issue 5 Page 546 - October 2004
Blackwell Synergy Publishing
Abstract
Objectives: At present, there are no diagnostic tools that permit early detection of peri-implantitis. The purpose of this cross-sectional study was to evaluate the correlation of myeloperoxidase (MPO) levels with traditional periodontal clinical parameters around dental implants including peri-implant pocket probing depth (PPD), gingival index (GI) and bleeding on probing (BOP), since MPO has been associated with destruction of periodontal tissues.
Material and methods: Twenty-four healthy adult volunteers (9 men and 15 women) with 64 Ankylos¨? Biofunctional implants (DentsplyFriadent, Mannheim, Germany) were recruited from Tallinn Dental Clinic. Biochemical and clinical parameters evaluated were the following ones: the level of MPO in the peri-implant sulcus fluid (PISF) (an analog for gingival crevicular fluid in natural teeth), PPD (mm), GI (0,1,2 or 3), and BOP (0 or 1).
Results and conclusion: In comparison to the clinically healthy implants, total amounts of MPO were significantly higher in PISF collected around implants with inflammatory lesions. In addition, the levels of MPO were correlated with the clinical parameters. The results confirm the similarity of the inflammatory response of tissues surrounding implants and natural teeth, and suggest that MPO could be promising marker of inflammation around dental implants.
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